Welcome to the Lazzaro Lab at Cornell University! Our work is focused on the evolutionary genetics of insect-pathogen interactions. Our projects include population genomic and molecular evolutionary analysis of insect immune systems and quantitative genetic study of differences in immune performance among individuals in a population. We seek to identify the genes responsible for individual differences in resistance or susceptibility to infection and environmental factors that influence defense. We are determining how genotype and environment interact to determine defense traits, and how seemingly distinct physiological processes are genetically linked and may constrain each other. At the same time, we note that the host is itself the "habitat" in which the pathogen lives and grows. We would like to understand how pathogens achieve infection of the host, and how host genotype and environment shape infection kinetics from the perspective of the pathogen. Our overarching goal is to consider host and pathogen as interacting components of a single system, shaped by the environment, that ultimately determines the outcome of infection and disease.
Read more at our Research page.

About the Principal Investigator

Brian P. Lazzaro, Professor
Department of Entomology, Cornell University
B.S., Genetics, 1995
University of California, Davis

Ph.D., Population Genetics, 2002
Pennsylvania State University

Curriculum vitae
Our lab accepts graduate students through the Graduate Training Fields of Entomology, Genetics & Development, Ecology & Evolutionary Biology, and Comparative Biomedical Sciences.

I teach a course in Ecological Genetics and am one of multiple instructors involved in teaching introductory Evolutionary Biology and Diversity. I am also a member of the test development committee that writes the AP Biology exam for US high school students.
Lazzaro Lab News

Lazzaro Lab Research Featured by Cornell

Despite the somewhat sinister photo chosen by the Cornell Research office, the lab has recently gotten some really good press from various Cornell outlets.

Check out this feature put out by the Cornell Research office on Brian's research program.

Cornell Research also did a feature story on Eliana's work in the lab. Eliana was additionally featured in the Cornell Chronicle earlier this year.

CALS and Cornell Entomology shot a video on the experience of being in the Lazzaro Lab, and along the way, a outtake grew into this video on how to remove fruit flies from your kitchen (incidentally, malt vinegar with a drop of liquid soap works even better than the trap described in the video).

Lazzaro Lab News archive