Welcome to the Lazzaro Lab at Cornell University! Our work is focused on the evolutionary genetics of insect-pathogen interactions. Our projects include population genomic and molecular evolutionary analysis of insect immune systems and quantitative genetic study of differences in immune performance among individuals in a population. We seek to identify the genes responsible for individual differences in resistance or susceptibility to infection and environmental factors that influence defense. We are determining how genotype and environment interact to shape defense traits, and how seemingly distinct physiological processes are genetically linked and may constrain each other. We are especially interested in the effects of dietary nutrition and metabolism, gut microbiological communities, and reproductive status on immune performance. We use molecular tools and genomic analysis in our research. Read more at our Research page.

About the Principal Investigator

Brian P. Lazzaro, Associate Professor
Department of Entomology, Cornell University
B.S., Genetics, 1995
University of California, Davis

Ph.D., Population Genetics, 2002
Pennsylvania State University

Curriculum vitae
Our lab accepts graduate students through the Graduate Training Fields of Entomology, Genetics & Development, Ecology & Evolutionary Biology, and Comparative Biomedical Sciences.

I teach a course in Ecological Genetics and am one of multiple instructors involved in teaching introductory Evolutionary Biology and Diversity.
Lazzaro Lab News

Filming JoVE


Sarah, Eliana and Moria filmed a methods article for Journal of Visualized Experimetns in February 2015. The piece illustrates a couple of different methods for delivering bacterial infections to Drosophila and quantifying post-infection phenotypes like systemic pathogen load, induction of immune response genes, and time to host death. More pictures here and the full video should be available soon.

Lazzaro Lab News archive